Rebuttal: Adaptive Point Mutation (Rosenberg and Hastings)
نویسندگان
چکیده
منابع مشابه
Rebuttal: adaptive point mutation (Rosenberg and Hastings).
The Rosenberg-Hastings paper (4) defends a model much like that of Foster (1) and argues that the observed mutagenesis contradicts predictions of the amplification model. On the contrary, amplification indirectly causes weak mutagenesis and allows that mutagenesis to have a detectable effect on lac reversion. However, this mutagenesis is a minor side effect that is neither sufficient nor necess...
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If mutations arose in nongrowing cells, as proposed in Foster’s paper (1), then stress-induced mutagenesis would seem inescapable. The plated population certainly grows very little. However, no evidence is provided that reversion occurs in this population and no effort is made to counter evidence to the contrary (see below)—that mutations actually arise in cells growing under selection within d...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 2004
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.186.15.4845.2004